Discourses

Discourse: Photodynamic Therapy: Physicists and physicians unite to heal with light

Laser expert Stephen Bown explores the physics of Photodynamic Therapy, and the new treatments it might unlock.

Tomás Mendes via Unsplash

Photodynamic Therapy (PDT) is offering a revolutionary new treatment option for a range of diseases, particularly cancers. By combining the skills of physicists and physicians, PDT uses light to kill living cells without damaging the structural integrity of the surrounding tissue.

In this Discourse, laser medicine expert Stephen Bown draws on his decades of experience to explain how PDT works. Administering the drugs (photosensitisers) that sensitise tissues to light is relatively straightforward, but getting light to all relevant areas deep within the body is a major challenge. Endoscopes provide access to hollow organs, but ingenuity and detailed understanding of light scattering and absorption within solid tissues is required to deliver appropriate light doses everywhere within a target tissue.

Stephen will further describe associated leading-edge developments, including cancer detection by photosensitiser fluorescence, the use of PDT as a “primer” to stimulate immunological responses to cancers and, at a very early stage of development, the concept that PDT might be able to offer a new approach to treating type 2 diabetes. Join us to discover one of the most exciting areas of development in clinical science.

Event type

This is a theatre and livestream event for an adult audience, where the speakers and audience in our Theatre are joined by our audience online. 

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For any queries regarding this event please get in touch by phone 020 7409 2992 or email events@ri.ac.uk.

This is an event at the Ri. 

About Stephen Bown

Prof Stephen Bown
Stephen G Bown

After a BA in Natural Sciences in Cambridge and a Masters in Physics at Harvard, Prof Stephen Bown returned to Cambridge, and subsequently UCL, to study Medicine. This led him to an academic career as a Consultant Gastroenterologist, Prof of Laser Medicine and Surgery and founder of the National Medical Laser Centre in UCL. 

He has given invited lectures in more than 40 countries and individuals from many countries have undertaken laboratory and clinical laser-related research projects in London under his supervision.

Stephen's connection with the Royal Institution dates back to 1981, when he gave his first Discourse, and he was featured as a guest expert in lasers in the Christmas Lectures in 1987. He has always worked to bring together scientists and clinicians to understand each other’s worlds, to enhance the understanding of the interaction of light with living tissue and to establish new therapeutic options.

Timing

Doors to the Theatre will open at about 6.50pm.

All attendees must be seated in the Theatre by 7.20pm. The Discourse will start promptly at 7.30pm.

A Pay Bar will be available from 6.00pm.

 

More about Discourses

Discourses are one of the Ri’s oldest and most prestigious series of talks. Since 1825, audiences in the theatre have witnessed countless mind-expanding moments, including the first public liquefaction of air by James Dewar, the announcement of the electron by JJ Thomson and over 100 lectures by Michael Faraday. In more recent times, we have had Nobel laureates, Fields medal winners, scientists, authors and artists – all from the leading-edge of their field. Discourses are an opportunity for the best and brightest to share their work with the world.

Steeped in two centuries of tradition, a Discourse is more than just a lecture. To keep the focus on the topic, presenters begin sharply at 7:30pm without introduction and we lock the speaker into a room ten minutes ahead of the start (legend has it that a speaker once tried to escape!). Some of our guests dress smartly for our Discourse events to add to this sense of occasion.

Find out more about the history of the Friday Evening Discourses on our blog.

Accessibility

The event will take place on the first floor and there is step-free access from the street via lift.

The closest underground station is Green Park, which is step-free.

There is space at floor level in the theatre for wheelchair users.

Seating is usually unreserved for our events. If you and your group require seating reservations, please do let us know by emailing us at events@ri.ac.uk, and we’ll be more than happy to help.

Carers can receive a free ticket to an event by emailing events@ri.ac.uk.

Our theatre is equipped with an Audio Induction Loop. 

Event terms and conditions